NSUN2 Antibody - N-terminal region, Rabbit, Polyclonal

Produktübersicht

• Artikelname: NSUN2 Antibody - N-terminal region, Rabbit, Polyclonal
• Artikelnummer: ASB-ARP48810_P050
• Hersteller Artikelnummer: ARP48810_P050
• Alternativnummer: ASB-ARP48810_P050-25UL, ASB-ARP48810_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NSUN2
• Alternative Synonym: MISU, MRT5, SAKI, TRM4

Produktbeschreibung

NSUN2 is a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. And it is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 84kDa
• NCBI: 54888
• UniProt: Q08J23
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.