MAP4K4 Antibody - N-terminal region
Artikelnummer:
ASB-ARP49031_P050
- Bilder (5)
| Artikelname: | MAP4K4 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP49031_P050 |
| Hersteller Artikelnummer: | ARP49031_P050 |
| Alternativnummer: | ASB-ARP49031_P050-25UL,ASB-ARP49031_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K4 |
| Alternative Synonym: | HGK, NIK, MEKKK4, FLH21957, HEL-S-31 |
| MAP4K4 is the serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. MAP4K4 appears to act upstream of the JUN N-terminal pathway.The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. |
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Liver |
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WB Suggested Anti-MAP4K4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Human Small Intestine |
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Host: Rabbit Target Name: MAP4K4 Sample Tissue: Human Stomach Tumor Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target: MAP4K4 Positive control (+): HepG2 Cell Lysate (HG) Negative control (-): Human Fetal Heart (HE) Antibody concentration: 1ug/ml |
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MAP4K4 antibody - N-terminal region (ARP49031_P050) in Human Stomach Tumor using Western Blot |
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