SEMA6D Antibody - N-terminal region
Artikelnummer:
ASB-ARP49583_P050
- Bilder (5)
| Artikelname: | SEMA6D Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP49583_P050 |
| Hersteller Artikelnummer: | ARP49583_P050 |
| Alternativnummer: | ASB-ARP49583_P050-25UL,ASB-ARP49583_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human SEMA6D |
| Alternative Synonym: | FLJ11598, KIAA1479 |
| Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. |
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WB Suggested Anti-SEMA6D Antibody Titration: 0.2-1 ug/ml Positive Control: Hela cell lysate |
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Host: Rabbit Target Name: SEMA6D Sample Type: Human Adult Placenta Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target Name: SEMA6D Sample Type: Human Fetal Heart Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target Name: SEMA6D Sample Type: Human Fetal Lung Antibody Dilution: 1.0ug/ml |
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SEMA6D antibody - N-terminal region (ARP49583_P050) in Human HeLa using Western Blot |
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