PAXIP1 Antibody - N-terminal region, Rabbit, Polyclonal

Produktübersicht

• Artikelname: PAXIP1 Antibody - N-terminal region, Rabbit, Polyclonal
• Artikelnummer: ASB-ARP51642_P050
• Hersteller Artikelnummer: ARP51642_P050
• Alternativnummer: ASB-ARP51642_P050-25UL, ASB-ARP51642_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAXIP1
• Alternative Synonym: PTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L

Produktbeschreibung

PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 74kDa
• NCBI: 22976
• UniProt: Q6ZW49
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.