TXNIP Antibody - C-terminal region

Artikelnummer: ASB-ARP52193_P050
Artikelname: TXNIP Antibody - C-terminal region
Artikelnummer: ASB-ARP52193_P050
Hersteller Artikelnummer: ARP52193_P050
Alternativnummer: ASB-ARP52193_P050-25UL,ASB-ARP52193_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TXNIP
Alternative Synonym: THIF, VDUP1, ARRDC6, HHCPA78, EST01027
TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 44kDa
NCBI: 10628
UniProt: Q9H3M7
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-TXNIP Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human heart
Host: Rabbit
Target Name: TXNIP
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml
Host: Rabbit
Target Name: TXNIP
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml
Host: Rabbit
Target Name: TXNIP
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml
Researcher: Anonymous
Application: Western Blotting
Species + Tissue/Cell type: Lane 1: 20ug mouse mesenchymal stem cell lysate
Primary antibody dilution: 1:2000
Secondary antibody: Anti-rabbit-HRP
Secondary antibody dilution: 1:10,000
TXNIP antibody - C-terminal region (ARP52193_P050) in Human Fetal Lung using Western Blot