METAP2 Antibody - N-terminal region

Produktübersicht

• Artikelname: METAP2 Antibody - N-terminal region
• Artikelnummer: ASB-ARP52266_P050
• Hersteller Artikelnummer: ARP52266_P050
• Alternativnummer: ASB-ARP52266_P050-25UL,ASB-ARP52266_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human METAP2
• Alternative Synonym: MAP2, MNPEP, p67eIF2

Produktbeschreibung

METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site.This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 53kDa
• NCBI: 10988
• UniProt: P50579
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. METAP2 Antibody (ARP52266_P050) concentration is 5 ug/ml.

WB Suggested Anti-METAP2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human brain

Host: Rabbit
Target Name: METAP2
Sample Type: Jurkat
Antibody Dilution: 1.0ug/mlMETAP2 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells

METAP2 antibody - N-terminal region (ARP52266_P050) in Human brain using Western Blot