IL1B Antibody - N-terminal region

Produktübersicht

• Artikelname: IL1B Antibody - N-terminal region
• Artikelnummer: ASB-ARP54324_P050
• Hersteller Artikelnummer: ARP54324_P050
• Alternativnummer: ASB-ARP54324_P050-25UL,ASB-ARP54324_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IL1B
• Alternative Synonym: IL-1, IL1F2, IL1beta, IL1-BETA

Produktbeschreibung

IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. The gene encoding IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 17kDa
• NCBI: 3553
• UniProt: P01584
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Human Macrophage

WB Suggested Anti-IL1B Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Placenta

Host: Rabbit
Target Name: IL1B
Sample Tissue: Human Stomach Tumor
Antibody Dilution: 1ug/ml

IL1B antibody - N-terminal region (ARP54324_P050) in Human Placenta using Western Blot