PRKCH Antibody - N-terminal region

Produktübersicht

• Artikelname: PRKCH Antibody - N-terminal region
• Artikelnummer: ASB-ARP56703_P050
• Hersteller Artikelnummer: ARP56703_P050
• Alternativnummer: ASB-ARP56703_P050-25UL,ASB-ARP56703_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCH
• Alternative Synonym: PKCL, PKC-L, PRKCL, nPKC-eta

Produktbeschreibung

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 78 kDa
• NCBI: 5583
• UniProt: P24723
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

WB Suggested Anti-PRKCH Antibody
Titration: 1.0 ug/ml
Positive Control: Jurkat Whole CellPRKCH is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells

Host: Rabbit
Target Name: PRKCH
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml

Host: Mouse
Target Name: PRKCH
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml

25 ug of HepG2 and whole cell extract was loaded onto a 12% SDS-PAGE gel. Blot was incubated with 3 ug/mL of antibody.

PRKCH antibody - N-terminal region (ARP56703_P050) in Human Jurkat using Western Blot