The immunogen is a synthetic peptide directed towards the N terminal region of human GPR56
Alternative Synonym:
BFPP, BPPR, GPR56, TM7LN4, TM7XN1
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants.