ADSL Antibody - middle region

Produktübersicht

• Artikelname: ADSL Antibody - middle region
• Artikelnummer: ASB-ARP59971_P050
• Hersteller Artikelnummer: ARP59971_P050
• Alternativnummer: ASB-ARP59971_P050-25UL,ASB-ARP59971_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ADSL
• Alternative Synonym: ASL, AMPS, ASASE

Produktbeschreibung

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 55kDa
• NCBI: 158
• UniProt: P30566
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Rabbit Anti-ADSL Antibody
Catalog Number: ARP59971_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic in endothelial cells in blood vessels
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

WB Suggested Anti-ADSL Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Muscle

Sample Type: 1. Hamster CHO K1 cells (20ug)
2. HeLa skin cells(100ug)
3. HEK273 cells (100ug)
4. HepG2 cells (100ug)
5. purified human ADSL protein (40ng)
Primary Dilution: 1:2000
Secondary Antibody: Clean-Blot IP detection Reagent and Kit
Secondary Dilution: 1:2000
Image Submitted By: V. Skopova, M. Zikanova
Institute of Inherited Metabolic Disorders, Charles University in Prague and General Hopspital in Prague ,

Host: Rabbit
Target Name: ADSL
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

ADSL antibody - middle region (ARP59971_P050) in Human Muscle using Western Blot