KPNB1 Antibody - N-terminal region

Produktübersicht

• Artikelname: KPNB1 Antibody - N-terminal region
• Artikelnummer: ASB-ARP61178_P050
• Hersteller Artikelnummer: ARP61178_P050
• Alternativnummer: ASB-ARP61178_P050-25UL,ASB-ARP61178_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
• Alternative Synonym: IMB1, IPO1, IPOB, Impnb, NTF97

Produktbeschreibung

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 96kDa
• NCBI: 3837
• UniProt: Q14974
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

WB Suggested Anti-KPNB1 Antibody
Titration: 1.0 ug/ml
Positive Control: ACHN Whole CellThere is BioGPS gene expression data showing that KPNB1 is expressed in ACHN

WB Suggested Anti-KPNB1 Antibody
Positive Control: Lane 1: 80ug mouse brain extractLane 2: 80ug rat brain extract
Primary Antibody Dilution : 1:500
Secondary Antibody : IRDye 800 CW goat anti-rabbit from Li-COR Bioscience
Secondry Antibody Dilution : 1:20,000
Submitted by: Dr. Yuzhi Chen, University of Arkansas for Medical Science

KPNB1 antibody - N-terminal region (ARP61178_P050) in Human ACHN using Western Blot