SLC7A5 Antibody - N-terminal region

Produktübersicht

• Artikelname: SLC7A5 Antibody - N-terminal region
• Artikelnummer: ASB-ARP63651_P050
• Hersteller Artikelnummer: ARP63651_P050
• Alternativnummer: ASB-ARP63651_P050-25UL,ASB-ARP63651_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Human
• Alternative Synonym: E16, CD98, LAT1, 4F2LC, MPE16, D16S469E

Produktbeschreibung

SLC7A5 is a sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. SLC7A5 is involved in cellular amino acid uptake. SLC7A5 acts as an amino acid exchanger. SLC7A5 is involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. SLC7A5 plays a role in neuronal cell proliferation (neurogenesis) in brain. SLC7A5 is involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. SLC7A5 is involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. SLC7A5 may play an important role in high-grade gliomas. SLC7A5 mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. SLC7A5 acts as the major transporter of tyrosine in fibroblasts.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 56kDa
• NCBI: 8140
• UniProt: Q01650
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

WB Suggested Anti-SLC7A5 Antibody
Titration: 1.0 ug/ml
Positive Control: Jurkat Whole Cell

Host: Rabbit
Target Name: SLC7A5
Sample Type: Human HepG2
Antibody Dilution: 1.0ug/mlSLC7A5 is supported by BioGPS gene expression data to be expressed in HepG2

Host: Rabbit
Target Name: SLC7A5
Sample Type: Human 721_B
Antibody Dilution: 1.0ug/mlSLC7A5 is supported by BioGPS gene expression data to be expressed in 721_B

Host: Rabbit
Target Name: SLC7A5
Sample Type: Human Hela
Antibody Dilution: 1.0ug/mlSLC7A5 is supported by BioGPS gene expression data to be expressed in HeLa

SLC7A5 antibody - N-terminal region (ARP63651_P050) in Human Jurkat using Western Blot