MAPK8 Antibody - N-terminal region

Produktübersicht

• Artikelname: MAPK8 Antibody - N-terminal region
• Artikelnummer: ASB-ARP77938_P050
• Hersteller Artikelnummer: ARP77938_P050
• Alternativnummer: ASB-ARP77938_P050-25UL,ASB-ARP77938_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAPK8
• Alternative Synonym: JNK, JNK1, PRKM8, SAPK1, JNK-46, JNK1A2, SAPK1c, JNK21B1/2

Produktbeschreibung

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 48 kDa
• NCBI: 5599
• UniProt: P45983
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Rabbit Anti-MAPK8 Antibody
Catalog Number: ARP77938_P050
Formalin Fixed Paraffin Embedded Tissue: Human Thyroid Gland Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

Host: Rabbit
Target Name: MAPK8
Sample Tissue: Human DLD1 Whole Cell
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: MAPK8
Sample Tissue: Human HepG2 Whole Cell
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: MAPK8
Sample Tissue: Human OVCAR-3 Whole Cell
Antibody Dilution: 1ug/ml

MAPK8 Antibody - N-terminal region (ARP77938_P050) in Human DLD1 Whole Cell using Western Blot