USP11 Antibody - N-terminal region
Artikelnummer:
ASB-ARP96748_P050
- Bilder (0)
| Artikelname: | USP11 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP96748_P050 |
| Hersteller Artikelnummer: | ARP96748_P050 |
| Alternativnummer: | ASB-ARP96748_P050-25UL,ASB-ARP96748_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human USP11 |
| Alternative Synonym: | UHX1 |
| Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Cleaves preferentially Lys-6 and Lys-63-linked ubiquitin chains. Has lower activity with Lys-11 and Lys-33-linked ubiquitin chains, and extremely low activity with Lys-27, Lys-29 and Lys-48-linked ubiquitin chains (in vitro). Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks. Acts as a chromatin regulator via its association with the Polycomb group (PcG) multiprotein PRC1-like complex, may act by deubiquitinating components of the PRC1-like complex. |
Produktgarantie und fachkundiger Support
