CAST Antibody - middle region
Artikelnummer:
ASB-ARP96787_P050
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| Artikelname: | CAST Antibody - middle region |
| Artikelnummer: | ASB-ARP96787_P050 |
| Hersteller Artikelnummer: | ARP96787_P050 |
| Alternativnummer: | ASB-ARP96787_P050-25UL,ASB-ARP96787_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle terminal region of human CAST |
| Alternative Synonym: | BS-17, PLACK |
| The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. |
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