ADAMTS2 Antibody - middle region
Artikelnummer:
ASB-ARP96801_P050
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| Artikelname: | ADAMTS2 Antibody - middle region |
| Artikelnummer: | ASB-ARP96801_P050 |
| Hersteller Artikelnummer: | ARP96801_P050 |
| Alternativnummer: | ASB-ARP96801_P050-25UL,ASB-ARP96801_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle terminal region of human ADAMTS2 |
| Alternative Synonym: | NPI, PNPI, PCINP, PCPNI, PCI-NP, PC I-NP, ADAM-TS2, ADAMTS-2, ADAMTS-3, EDSDERMS |
| This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
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