USP14 Antibody - C-terminal region
Artikelnummer:
ASB-ARP96866_P050
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| Artikelname: | USP14 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP96866_P050 |
| Hersteller Artikelnummer: | ARP96866_P050 |
| Alternativnummer: | ASB-ARP96866_P050-25UL,ASB-ARP96866_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human USP14 |
| Alternative Synonym: | TGT |
| This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
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