ATP1A2 Antibody - N-terminal region
Artikelnummer:
ASB-ARP96897_P050
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| Artikelname: | ATP1A2 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP96897_P050 |
| Hersteller Artikelnummer: | ARP96897_P050 |
| Alternativnummer: | ASB-ARP96897_P050-25UL,ASB-ARP96897_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human ATP1A2 |
| Alternative Synonym: | FHM2, MHP2 |
| The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. |
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