MICALL2 Antibody - C-terminal region

Artikelnummer: ASB-ARP97076_P050
Artikelname: MICALL2 Antibody - C-terminal region
Artikelnummer: ASB-ARP97076_P050
Hersteller Artikelnummer: ARP97076_P050
Alternativnummer: ASB-ARP97076_P050-25UL,ASB-ARP97076_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Human
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MICALL2
Alternative Synonym: JRAB, MICAL-L2
Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth (By similarity).
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 99 kDa
NCBI: 79778
UniProt: Q8IY33
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.