NFKBIA Antibody - N-terminal region
Artikelnummer:
ASB-ARP97310_P050
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| Artikelname: | NFKBIA Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP97310_P050 |
| Hersteller Artikelnummer: | ARP97310_P050 |
| Alternativnummer: | ASB-ARP97310_P050-25UL,ASB-ARP97310_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human NFKBIA |
| Alternative Synonym: | IKBA, MAD-3, NFKBI, EDAID2 |
| This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. |
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