The immunogen is a synthetic peptide directed towards the N terminal region of mouse ITGAX
Alternative Synonym:
Cr4, N418, Cd11c, AI449405
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis (By similarity).