GNRHR Antibody - N-terminal region
Artikelnummer:
ASB-ARP97896_P050
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| Artikelname: | GNRHR Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP97896_P050 |
| Hersteller Artikelnummer: | ARP97896_P050 |
| Alternativnummer: | ASB-ARP97896_P050-25UL,ASB-ARP97896_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human GNRHR |
| Alternative Synonym: | HH7, GRHR, LRHR, LHRHR, GNRHR1 |
| This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5 region and multiple polyA signals in the 3 region have been identified for this gene. |
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