MAPK14 Antibody - C-terminal region

Produktübersicht

• Artikelname: MAPK14 Antibody - C-terminal region
• Artikelnummer: ASB-AVARP06004_P050
• Hersteller Artikelnummer: AVARP06004_P050
• Alternativnummer: ASB-AVARP06004_P050-25UL,ASB-AVARP06004_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MAPK14
• Alternative Synonym: RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA

Produktbeschreibung

MAPK14 encodes a protein which is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 41kDa
• NCBI: 1432
• UniProt: Q16539
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Human Liver

Rabbit Anti-MAPK14 Antibody
Catalog Number: AVARP06004_P050
Formalin Fixed Paraffin Embedded Tissue: Human Bone Marrow Tissue
Observed Staining: Cytoplasm, Nucleus
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

WB Suggested Anti-MAPK14 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysateMAPK14 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells

Host: Mouse
Target Name: MAPK14
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: MAPK14
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 1ug/ml

MAPK14 antibody - C-terminal region (AVARP06004_P050) in Human Jurkat using Western Blot