The immunogen is a synthetic peptide directed towards the N terminal region of human KDR
Alternative Synonym:
FLK1, CD309, VEGFR, VEGFR2
KDR is the receptor for VEGF or VEGFC. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions.