This LCLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids of human LCLT1.
Alternative Synonym:
LYCAT, AGPAT8, ALCAT1, 1AGPAT8, UNQ1849, HSRG1849
Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.
