IDH1 Antibody - N-terminal region
Artikelnummer:
ASB-OAAB04488
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| Artikelname: | IDH1 Antibody - N-terminal region |
| Artikelnummer: | ASB-OAAB04488 |
| Hersteller Artikelnummer: | OAAB04488 |
| Alternativnummer: | ASB-OAAB04488-400UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | FC, IF, IHC-P, WB |
| Spezies Reaktivität: | Human, Mouse |
| Immunogen: | This IDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the N-terminal region of human IDH1. |
| Alternative Synonym: | IDH, IDP, IDCD, IDPC, PICD, HEL-216, HEL-S-26 |
| IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. |
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