GHRH Antibody - N-terminal region
Artikelnummer:
ASB-OAAB04805
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| Artikelname: | GHRH Antibody - N-terminal region |
| Artikelnummer: | ASB-OAAB04805 |
| Hersteller Artikelnummer: | OAAB04805 |
| Alternativnummer: | ASB-OAAB04805-400UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IF, IHC-P, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | This GHRH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-34 amino acids from the N-terminal region of human GHRH. |
| Alternative Synonym: | GRF, INN, GHRF |
| GHRH belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this protein are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. |
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