LMCD1 Antibody - C-terminal region
Artikelnummer:
ASB-OAAB19068
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| Artikelname: | LMCD1 Antibody - C-terminal region |
| Artikelnummer: | ASB-OAAB19068 |
| Hersteller Artikelnummer: | OAAB19068 |
| Alternativnummer: | ASB-OAAB19068-400UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Immunogen: | This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1. |
| Alternative Synonym: | LIM and cysteine-rich domains protein 1, Dyxin, LMCD1 |
| Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway. |
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