CHD3 Antibody, IgG1, Clone: [2G4], Mouse, Monoclonal
Artikelnummer:
ASB-OAAD00334
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| Artikelname: | CHD3 Antibody, IgG1, Clone: [2G4], Mouse, Monoclonal |
| Artikelnummer: | ASB-OAAD00334 |
| Hersteller Artikelnummer: | OAAD00334 |
| Alternativnummer: | ASB-OAAD00334-0.1ML |
| Hersteller: | Aviva |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF, IHC, WB |
| Spezies Reaktivität: | Human, Mouse |
| Immunogen: | Purified recombinant fragment of human CHD3 expressed in E. Coli. |
| Alternative Synonym: | ZFH, Mi-2a, SNIBCPS, Mi2-ALPHA |
| This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. |
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