FOXP3 Antibody, IgG1, Clone: [4C7], Mouse, Monoclonal
Artikelnummer:
ASB-OAAD00367
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| Artikelname: | FOXP3 Antibody, IgG1, Clone: [4C7], Mouse, Monoclonal |
| Artikelnummer: | ASB-OAAD00367 |
| Hersteller Artikelnummer: | OAAD00367 |
| Alternativnummer: | ASB-OAAD00367-0.1ML |
| Hersteller: | Aviva |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Purified recombinant fragment of human FOXP3 expressed in E. Coli. |
| Alternative Synonym: | JM2, AIID, IPEX, PIDX, XPID, DIETER |
| FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells. |
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