Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.
Alternative Synonym:
Bcl-2, PPP1R50
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.Tissue specificity: Expressed in a variety of tissues.