ESR1 Antibody, IgG1, Clone: [6B6], Mouse, Monoclonal
Artikelnummer:
ASB-OAAD00374
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| Artikelname: | ESR1 Antibody, IgG1, Clone: [6B6], Mouse, Monoclonal |
| Artikelnummer: | ASB-OAAD00374 |
| Hersteller Artikelnummer: | OAAD00374 |
| Alternativnummer: | ASB-OAAD00374-0.1ML |
| Hersteller: | Aviva |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | IF, IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Purified recombinant fragment of human ESR1 expressed in E. Coli. |
| Alternative Synonym: | ER, ESR, Era, ESRA, ESTRR, NR3A1 |
| This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. |
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