The antiserum was produced against synthesized peptide derived from human TM16A.
Alternative Synonym:
anoctamin 1, calcium activated chloride channel,anoctamin-1,Ca2+-activated Cl- channel,calcium activated chloride channel,discovered on gastrointestinal stromal tumors protein 1,DOG1,oral cancer overexpressed 2,Oral cancer overexpressed protein 2,ORAOV2,TAOS2,TMEM16A,Transmembrane protein 16A,transmembrane protein 16A (eight membrane-spanning domains),tumor-amplified and overexpressed sequence 2.
Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
