The antiserum was produced against synthesized peptide derived from human STEAP4.
Alternative Synonym:
metalloreductase STEAP4,SchLAH,seven chromosome locus associated with HCC,six transmembrane prostate protein 2,six-transmembrane epithelial antigen of prostate 4,sixTransMembrane protein of prostate 2,STAMP2,STEAP family member 4,TIARP,TNFAIP9,tumor necrosis factor, alpha-induced protein 9,tumor necrosis-alpha-induced adipose-related protein.
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+) (By similarity). Uses NADP(+) as acceptor (By similarity). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance (PubMed:18430367, PubMed:18381574). Involved in inflammatory arthritis, through the regulation of inflammatory cytokines (PubMed:19660107). Inhibits anchorage-independent cell proliferation (PubMed:19787193).
