PVRL3 Antibody, Rabbit, Polyclonal
Artikelnummer:
ASB-OAAF08108
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| Artikelname: | PVRL3 Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ASB-OAAF08108 |
| Hersteller Artikelnummer: | OAAF08108 |
| Alternativnummer: | ASB-OAAF08108-100UG |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human PVRL3. |
| Alternative Synonym: | CD113,CDW113,nectin 3,Nectin cell adhesion molecule 3,nectin-3,poliovirus receptor-related 3,poliovirus receptor-related protein 3,PPR3,PRR3,PVRL3,PVRR3. |
| Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body. |
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