HDAC6 Antibody, Clone: [ABT-HDAC6], Mouse, Monoclonal

Produktübersicht

• Artikelname: HDAC6 Antibody, Clone: [ABT-HDAC6], Mouse, Monoclonal
• Artikelnummer: ASB-OAAF08309
• Hersteller Artikelnummer: OAAF08309
• Alternativnummer: ASB-OAAF08309-0.1ML,ASB-OAAF08309-0.05ML
• Hersteller: Aviva
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide
• Alternative Synonym: CPBHM,HD6,histone deacetylase 6,JM21,PPP1R90,protein phosphatase 1, regulatory subunit 90,tubulin-lysine deacetylase HDAC6.

Produktbeschreibung

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [ABT-HDAC6]
• Molekulargewicht: 131 kDa
• NCBI: 10013
• UniProt: Q9UBN7
• Formulierung: PBS, pH7.2, 0.03% Proclin 300, 50% glycerol