CD146 Antibody, Rabbit, Polyclonal
Artikelnummer:
ASB-OAAI00040
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| Artikelname: | CD146 Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ASB-OAAI00040 |
| Hersteller Artikelnummer: | OAAI00040 |
| Alternativnummer: | ASB-OAAI00040-100UG |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FC, IHC, IP, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant human CD146 protein encoding aa 433-647 expressed in E.coli. |
| Alternative Synonym: | CD146,cell surface glycoprotein MUC18,cell surface glycoprotein P1H12,Gicerin,HEMCAM,melanoma adhesion molecule,melanoma-associated antigen A32,melanoma-associated antigen MUC18,MelCAM,METCAM,MUC18,S-endo 1 endothelial-associated antigen. |
| CD146 belongs to the immunoglobulin super-gene family with five immunoglobulin like domains (V-V-C2-C2-C2), a transmembrane region and a 63 residue cytoplasmic tail. The protein is a membrane glycoprotein that functions as a Ca2+ independent cell adhesion molecule involved in heterophilic cell to cell interactions. CD146 has a molecular size of 130 kDa in its reduced form (118 kDa unreduced), and N linked glycosylation accounts for fifty percent of the apparent molecular weight. In some cells the molecule carries a sulfate 3 glucuronyl moiety. |
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