Anti-STAT3 Antibody (Phospho-S 727), Rabbit, Polyclonal
Artikelnummer:
ASB-OAAI00081
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| Artikelname: | Anti-STAT3 Antibody (Phospho-S 727), Rabbit, Polyclonal |
| Artikelnummer: | ASB-OAAI00081 |
| Hersteller Artikelnummer: | OAAI00081 |
| Alternativnummer: | ASB-OAAI00081-100UG |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | FC, IHC, IP, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Immunogen: | A synthetic peptide surrounding to the epitope -PMSPR-- with phosphorylation sites at Ser727 of STAT3 protein from human, mouse, rat, chicken dog and bovine origins. |
| Alternative Synonym: | acute-phase response factor,ADMIO,ADMIO1,APRF,DNA-binding protein APRF,HIES,signal transducer and activator of transcription 3. |
| STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. The phosphorylation of STAT3 induces STAT dimerization, nuclear translocation and DNA binding. Stat3 is constitutively activated in a number of Human tumors. Stat3- activated transcription seems to be regulated by serine phosphorylation at Ser727. |
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