Anti-KeRatin-20 Polyclonal Antibody, Rabbit
Artikelnummer:
ASB-OAAI00119
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| Artikelname: | Anti-KeRatin-20 Polyclonal Antibody, Rabbit |
| Artikelnummer: | ASB-OAAI00119 |
| Hersteller Artikelnummer: | OAAI00119 |
| Alternativnummer: | ASB-OAAI00119-100UG |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FC, IHC, IP, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant protein encoding aa 230-425 of human keratin 20. |
| Alternative Synonym: | CD20,CK20,CK-20,cytokeratin 20,K20,keratin 20, type I,keratin, type I cytoskeletal 20,KRT21,protein IT. |
| KeRatins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeRatins and hair keRatins. KeRatin 20 / cytokeRatin20 (CK20) is a Type-I keRatin which is primarily expressed in gastric and intestinal epithelium, urothelium, and Merkel-cells. CK20 is expressed in adenocarcinomas of the colon, stomach, pancreas and the bile system. CK20 is also present in mucinous ovarian tumors, transitional-cell and Merkel-cell carcinomas. Notably, the squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors of the ovary, and small cell carcinomas lack in CK20. |
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