Anti-GluR6/7 Polyclonal Antibody, Rabbit
Artikelnummer:
ASB-OAAI00175
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| Artikelname: | Anti-GluR6/7 Polyclonal Antibody, Rabbit |
| Artikelnummer: | ASB-OAAI00175 |
| Hersteller Artikelnummer: | OAAI00175 |
| Alternativnummer: | ASB-OAAI00175-100UG |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FC, IHC, IP, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Immunogen: | A synthetic peptide derived from C-terminus of Glutamate receptor 6/7 Protein. This sequence is identical to human, mouse and rat. |
| Alternative Synonym: | bA487F5.1,EAA4,excitatory amino acid receptor 4,GLR6,GluK2,GluK2(alt_5UTR),GLUK6,gluR-6,GLUR6,glutamate receptor 6,glutamate receptor form A,glutamate receptor form B,glutamate receptor form C,glutamate receptor form D,glutamate receptor form E,glutamate receptor ionotropic, kainate 2,MRT6,putative NMDtranscript(cassette_171nt). |
| Glutamate receptors (GluR) are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Two classes of glutamate receptors exist: ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR1-7, NMDA1- 3, KAI-2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors. GluR6 belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thoµght to alter the structure and function of the receptor complex. Mutations in this gene have been associated with autosomal recessive mental retardation. |
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