Anti-MMP-9 Polyclonal Antibody, Rabbit
Artikelnummer:
ASB-OAAI00208
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| Artikelname: | Anti-MMP-9 Polyclonal Antibody, Rabbit |
| Artikelnummer: | ASB-OAAI00208 |
| Hersteller Artikelnummer: | OAAI00208 |
| Alternativnummer: | ASB-OAAI00208-100UG |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FC, IHC, IP, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | A synthetic peptide corresponding to the hinge of human MMP-9. |
| Alternative Synonym: | CLG4B,GELB,macrophage gelatinase,MANDP2,matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase),matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase),matrix metalloproteinase-9,MMP-9,type V collagenase. |
| Matrix metalloproteinases (MMPs) belong to a family of proteinases that target many extracellular matrix proteins including additional proteinases, growth factors, cell surface receptors and adhesion molecules. MMPs contain common domain structures that include a signal sequence, a propeptide, a catalytic domain, and a hemopexin-like (Hpx) domain. The MMP activity requires proteolytic cleavage of MMPs in order to geneRate activie MMPs by release of the inhibitory propeptide domain from the whole molecules. MMP-2, MMP-3, MMP-7, MMP-9 and MMP-13 have been characterized as important factors for normal tissue remodeling during embryo development and wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis. MMP activities are correlated with cancer metastatic process.MMP-2 and MMP-9, gelatinases, degrade basement membrane collagen. |
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