A synthetic peptide corresponding to C-terminus of OCT-2 protein from human, mouse and rat origins.
Alternative Synonym:
homeobox protein,lymphoid-restricted immunoglobulin octamer-binding protein NF-A2,Oct-2,OCT2,octamer-binding protein 2,octamer-binding transcription factor 2,OTF2,POU domain, class 2, transcription factor 2.
Oct1 and Oct2 are transcription factors of the POU homeo-domain family that bind to the lg gene octamer sites, regulating B-cell-specific genes. The function of these transcription factors is dependent on the activity of B-cell-restricted coactivators such as BOB.1/OBF.1.Absence of functional Oct-2 and Bob-1 cells represents a novel mechanism for immunoglobulin gene deregulation