TFAM Antibody, Rabbit, Polyclonal

Artikelnummer: ASB-OAAJ07170
Artikelname: TFAM Antibody, Rabbit, Polyclonal
Artikelnummer: ASB-OAAJ07170
Hersteller Artikelnummer: OAAJ07170
Alternativnummer: ASB-OAAJ07170-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant protein of human TFAM
Alternative Synonym: TCF6, MTTF1, MTTFA, TCF6L1, TCF6L2, TCF6L3, MTDPS15
Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.
Klonalität: Polyclonal
Konzentration: 1 mg/mL
Molekulargewicht: 29 kDa
NCBI: 7019
UniProt: Q00059
Formulierung: Liquid