The antibody was raised by immunising BALB/c mice with human alveolar macrophages (AMs) and subsequent creation of hybridomas.
Alternative Synonym:
macrophage receptor MARCO,Macrophage receptor with collagenous structure,SCARA2,Scavenger receptor class A member 2,scavenger receptor class A, member 2,SR-A6.
Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed:9468508). Also plays a role in binding of unopsonized particles by alveolar macrophages (By similarity). Binds to the secretoglobin SCGB3A2 (PubMed:12847263).
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