KLH conjugated synthetic peptide derived from human AMPK beta 1
Konjugation:
Unconjugated
Alternative Synonym:
5-AMP-activated protein kinase beta-1 subunit,5-AMP-activated protein kinase subunit beta-1,AMP-activated protein kinase beta subunit,AMPK,AMPK beta 1,AMPK beta -1 chain,AMPK subunit beta-1,AMPKb,HAMPKb,protein kinase, AMP-activated, beta 1 non-catalytic subunit,protein kinase, AMP-activated, noncatalytic, beta-1.
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
