Bovine, Canine, Equine, Human, Mouse, Porcine, Rat
Immunogen:
KLH conjugated synthetic peptide derived from human GLI1
Konjugation:
Unconjugated
Alternative Synonym:
GLI,GLI-Kruppel family member GLI1,Glioma-associated oncogene,glioma-associated oncogene 1,glioma-associated oncogene homolog 1 (zinc finger protein),oncogene GLI,PAPA8,PPD1,zinc finger protein GLI1.
Acts as a transcriptional activator (PubMed:19706761, PubMed:10806483, PubMed:19878745, PubMed:24311597, PubMed:24217340). Binds to the DNA consensus sequence 5-GACCACCCA-3 (PubMed:2105456, PubMed:8378770, PubMed:24217340). May regulate the transcription of specific genes during normal development (PubMed:19706761). May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling (PubMed:19706761). Plays a role in cell proliferation and differentiation via its role in SHH signaling (Probable).
