KLH conjugated synthetic peptide derived from human S100B
Konjugation:
Unconjugated
Alternative Synonym:
NEF,protein S100-B,S100,S100 calcium-binding protein B,S100 calcium-binding protein, beta (neural),S-100 calcium-binding protein, beta chain,S-100 protein beta chain,S-100 protein subunit beta,S100-B,S100beta.
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
