FAAR,NR1C2,NUC1,NUCI,NUCII,nuclear hormone receptor 1,nuclear receptor subfamily 1 group C member 2,peroxisome proliferator-activated receptor beta,peroxisome proliferator-activated receptor delta,PPARB,PPAR-beta,PPARD/MYO1D fusion,PPAR-delta.
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
