PPIE Antibody

Produktübersicht

• Artikelname: PPIE Antibody
• Artikelnummer: ASB-OACD06659
• Hersteller Artikelnummer: OACD06659
• Alternativnummer: ASB-OACD06659-100UL,ASB-OACD06659-1ML
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: ICC, IHC, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Range: Tyr41 - Val264
• Alternative Synonym: Cyclophilin E,cyclophilin-33,CYP33,CYP-33,peptidyl-prolyl cis-trans isomerase E,peptidylprolyl isomerase E (cyclophilin E),PPIase E,rotamase E.

Produktbeschreibung

Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28076346). Combines RNA-binding and PPIase activities (PubMed:8977107, PubMed:18258190, PubMed:20677832, PubMed:20460131). Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3-UTR of mRNA molecules (PubMed:8977107, PubMed:18258190, PubMed:20460131). Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins (PubMed:8977107, PubMed:18258190, PubMed:20677832, PubMed:20541251). Inhibits KMT2A activity, this requires proline isomerase activity (PubMed:20677832, PubMed:20541251, PubMed:20460131).

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 33 kDa
• NCBI: 10450
• Formulierung: Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.