AGR2 Antibody

Produktübersicht

• Artikelname: AGR2 Antibody
• Artikelnummer: ASB-OAEB01151
• Hersteller Artikelnummer: OAEB01151
• Alternativnummer: ASB-OAEB01151-100UG
• Hersteller: Aviva
• Wirt: Goat
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Canine, Human, Mouse
• Immunogen: AGR2
• Alternative Synonym: AG2,AG-2,Agr2h,anterior gradient 2 homolog,anterior gradient homolog 2,anterior gradient protein 2 homolog,epididymis secretory protein Li 116,Gob-,GOB-4,HAG-,HAG-2,HEL-S-116,HPC8,mAG-,mAG-2,PDIA17,protein disulfide isomerase family A, member 17,protein Gob-4,secreted cement gland homolog,secreted cement gland protein XAG-2 homolog,XAG-,XAG-2.

Produktbeschreibung

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 20
• NCBI: 23795, 10551
• Formulierung: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20AC. Minimize freezing and thawing.